The SweatC system is a programmable electro medical device comprised of a USB plug and play hardware unit (electronic box, cables, and 2 disposable electrodes), and software for the measurement of galvanic skin response.


The SweatC  measurement process uses the electrically induced quantitative sudomotor axon reflex tests method following DC stimulation at constant voltage of 1.28V, and provides quantitative evaluation of the sweat response measured on disposable electrodes .The quantitave induced sweat response is expressed in skin voltage response (SVR). The measurement is performed at the sole of the right and left feet, which have the highest density of eccrine sweat glands and C-fibers that travel the furthest from the brain and spinal cord.


Sudomotor dysfunction has been found in diabetic patients, medication side effects such as cancer treatment or antihypertensive treatment ( in particular Beta and Alpha blockers, and calcium antagonists), Metformin treatment, vitamin D or B12 deficiency, Parkinson’s disease, AISD, amyotrophic lateral sclerosis, hypothyroidism, kidney and liver diseases, alcoholism, Alzheimer's disease and Guillain-Barre syndrome.

The Sudomotor test evaluates autonomic function (the sympathetic cholinergic division) , and it is performed in a clinical setting to evaluate and document neuropathic disturbances that may be associated with pain or symptoms. Examples of Sudomotor testing include: The quantitative sudomotor axon reflex test (QSART), thermoregulatory sweat test (TST), sympathetic or galvanic skin responses, and silastic sweat imprints are tests of sympathetic cholinergic sudomotor function.

There exists over 60 years of data supporting the use of sudomotor testing in clinical practice, and the Sudomotor testing clinical data suggest it may be the most sensitive means to detect peripheral small fiber neuropathy (Low, et al.,2006) The exam is performed in supine position on exam table.

The use of large disposable (single use) electrodes prevents:

  • The cross contamination
  • The biased measurement from cold or hot metal reusable electrodes
  • The biased measurement from excessive pressure on the electrodes by the sitting or standing position.

Intended use and indications for use

SweatC is a medical device for the measurement of galvanic skin response related to the function of the sweat glands.
The SweatC device provides values. It is the physician's responsibility to make proper judgments based on these numbers.
The device is indicated for use with the general adult population.
Prescription Use Caution: Federal law restricts this device to sale by or on the order of a physician

FDA Clearance 510K number k152216