- Accuracy of the heart rate detection:
Comparing our algorithm using the first derivative of the photoplethysmography to EKG, the coefficient of correlation r=0.99.
-Accuracy of the HRV analysis:
According to the standard ANSI/AAMI EC57, our results are in compliance with the Input MIT-BIH database.
- Research and development i.e. clinical studies:
The PTG spectral analysis using LD-Oxy is patented.
PTG mathematical analysis markers were compared to:
- Gold standard of Insulin resistance assessment:
Hyperinsulinemic Euglycemic Clamp (HEC), PTG-TP marker returns a sensitivity = 95.7%, specificity = 84,4% and the area under the ROC curve (AUC) = 0.929 for identifying insulin resistance.
- Oral Glucose Tolerance Test (OGTT):
The correlations between the OGTT and photoplethysmography index (PTGi) were: r = - 0.56 (p = 0.003) for glucose and r = - 0.41 (p = 0.04)for insulin
- Coronary angiography:
PTGi returns a sensitivity of 86.1% and specificity of 87.1% and the area under the ROC curve ( AUC) = 0.926 for identifying endothelial function.